Nineteen of the Russian's twenty-one titles have been won on hard surfaces
A comeback Medvedev claimed his first trophy for over two years with success over opponent Moutet in the tournament final.
The athlete, a former world number one, has had a difficult period, winning just a single victory at the major tournaments and suffering a meltdown at the US Open.
Medvedev's inconsistency on the tennis tour - and difficulties with his service game in especial - caused him exiting of the world's top 10 and finally parting ways with former coach his previous coach.
Currently working with Johansson and his other coach, Medvedev has consistently improved in the past month - peaking in a closely contested competitive win over Frenchman Corentin Moutet.
It is his initial title following the Rome competition and first on a hard surface from that period of the previous year.
The win also signifies the Russian has secured twenty-one championships at twenty-one various events.
"For the first time I am participating in a event with my children at once, so to secure a championship is particularly special," said world number 14 the champion.
"This title is in dedication of my second daughter her name, because the first title I got when my older daughter Alisa was born was for her."
The tennis star, the past champion, had failed in his past six finals, comprising in Halle in the past months.
The player's counter-punching strategy and recurring reactions on the playing surface had led observers to question if his capacity to perform at the top level was over.
But the 29-year-old has implemented adjustments in the last few weeks, attempting to advance forward and play positively, reinforced by an enhanced service.
He came back from a deficit in the opening set against the tricky Moutet, taking 4 of the last five points to gain the advantage.
The pair traded service breaks in the following set before the Frenchman, attempting for his maiden professional victory, seized the initiative to force a decider.
The opponent saved 4 early opportunities in a tight third set before Medvedev won the break to that score to serve for the match.
Fittingly, he clinched the title with a rally at the front of the court, with Moutet unable to handle a return after over two and a half hours.
